加利福尼亚大学戴维斯分校Savithramma Dinesh-Kumar教授学术报告

报告题目：Emerging perspectives on plant innate immunity
时间: 2016年09月15日下午15：00
地点: 理科实验楼B702
报告人：Savithramma Dinesh-Kumar
报告人简介:Savithramma Dinesh-Kumar教授实验室主要从事植物免疫受体识别病原物以及植物如何启动免疫信号的分子机制研究，在烟草花叶病毒抗病基因N基因的抗病机制方面取得了丰厚的研究成果；此外，Dinesh-Kumar教授在细胞自噬在植物免疫反应和细胞死亡中的作用方面也开展了大量原创性工作。相应成果在Cell、Cell Host Microbe、The EMBO Journal、The plant cell 、PNAs、PLoS Pathogens、Developmental Cell、Autophagy等学术期刊上发表。
代表性论文：
1) Caplan, J., Kumar, AS., Park, E., Padmanabhan, MS., Hoban, K., Modla, S., Czymmek, K., and Dinesh-Kumar, SP (2015). Chloroplast stromules function during innate immunity. Dev Cell 34:45-57. (Cover article).
2) Woo J, Park E, and Dinesh-Kumar SP. (2014) Differential processing of Arabidopsis ubiquitin-like Atg8 autophagy proteins by Atg4 cysteine proteases. Proc. Natl. Acad. Sci. 111:863-868.
3) Padmanabhan M, Ma S, Burch-Smith T, Czymmek K, Huijser P, and Dinesh-Kumar SP. (2013) Novel Positive Regulatory Role for the SPL6 Transcription Factor in the N TIR-NB-LRR Receptor-Mediated Plant Innate Immunity. PLoS Pathogens 9(3):e1003235.
4) Zhu X, Caplan JC, Mamillapalli P, Czymmek K, and Dinesh-Kumar SP. (2010) Function of endoplasmic reticulum calcium ATPase in innate immunity mediated programmed cell death. EMBO J 29, 1007-1018.
5) *Caplan JC, *Zhu X, (contributed equally), Mamillapalli P, Marathe R, Anandalakshmi R, and Dinesh-Kumar SP. (2009) Induced ER-chaperones regulate a receptor-like kinase to mediate anti-viral innate immune response in plants. Cell Host Microbe 6, 457-469.
6) Caplan JC, Mamillapalli P, Burch-Smith TM, Czymmek K, and Dinesh-Kumar SP. (2008) Chloroplastic protein NRIP1 mediates innate immune receptor recognition of a viral effector. CELL 132:449-462.
7) Liu Y, Schiff M, Czymmek K, Talloczy Z, Levine B, and Dinesh-Kumar SP. (2005) Autophagy regulates programmed cell death during the plant innate immune response. Cell 121:567-577.
8) Liu Y, Schiff M, Serino G, Deng XW, and Dinesh-Kumar SP. (2002) Role of SCF ubiquitin-ligase and the COP9 signalosome in the N gene-mediated resistance response to Tobacco mosaic virus. Plant Cell. 14:1483-1496.
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